gallstones

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

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Study Counts

Type	Study_count
Total_Studies	152
interventional	108
Observational	37
Registry	7

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type	Study_Count
Procedure	59
Drug	13
Device	10
Other	6
Drug|placebo	5
Diagnostic Test	3
Behavioral	2
Device|Procedure	2
Drug|Other	2
Device|Drug|Radiation	1
Device|Other	1
Device|Other|Procedure	1
Dietary Supplement	1
Dietary Supplement|placebo	1
Other|Procedure	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	15
China	14
Egypt	9
NA	8
Turkey	6
Switzerland	5
Korea, Republic of	4
United Kingdom	4
Denmark	3
Finland	3
India	3
Italy	3
Netherlands	3
Austria	2
France	2
Germany	2
Greece	2
Israel	2
Spain	2
Sweden	2
Thailand	2
Canada	1
Cuba	1
Hong Kong	1
Italy|Switzerland	1
Malaysia	1
Mexico	1
Nepal	1
Serbia	1
Singapore	1
Taiwan	1
United States|Argentina|Germany|Italy|Japan	1
United States|India|Italy|Japan|Netherlands|Thailand	1

Sites per Study

Site_count	Study_Count
1	97
2	5
4	1
5	1
7	1
10	1
12	2

Phase

Phase	Study_Count
N/A	79
Phase 4	17
Phase 3	6
Phase 1	2
Phase 2	2
Phase 1/Phase 2	1
Phase 2/Phase 3	1

Number of Arms

Number_of_Arms	Count_of_Studies
1	14
2	79
3	11
4	2
NA	2

Enrollment Metrics by Phase

Measure	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	8.0	20.00	40	40.00	355	40.0000	20.0000
1st Qu.	50.0	25.25	40	61.25	355	60.0000	50.0000
Median	94.0	30.50	40	82.50	355	71.5000	80.0000
Mean	134.5	30.50	40	82.50	355	157.3333	111.8824
3rd Qu.	130.0	35.75	40	103.75	355	155.7500	115.0000
Max.	1196.0	41.00	40	125.00	355	521.0000	600.0000

Trial Group Type

group_type	Group_Count
Active Comparator	87
Experimental	82
Placebo Comparator	15
No Intervention	13
Other	13
Sham Comparator	3
NA	2

Intervention Model

intervention_model	Study_Count
Parallel Assignment	82
Single Group Assignment	19
Crossover Assignment	3
Factorial Assignment	3
NA	1

Primary Purpose

primary_purpose	Study_Count
Treatment	70
Diagnostic	12
Prevention	10
Other	6
Basic Science	4
NA	4
Health Services Research	1
Supportive Care	1

Observational Studies

Studies by Country

Country	Study_Count
United States	7
NA	6
China	4
Sweden	3
Chile	2
Finland	2
Switzerland	2
Denmark	1
Ireland|Italy|Portugal|Spain	1
Italy	1
Mexico	1
Norway	1
Pakistan	1
Spain	1
Taiwan	1
Thailand	1
Turkey	1
United Kingdom	1

Sites per Study

Site_count	Study_Count
1	29
2	6
5	1
6	1

Enrollment Metrics

Measure	Observational
Min	10.0000
1st Qu	141.0000
Median	218.0000
Mean	873.3514
3rd Qu	450.0000
Max	18064.0000

Observation Model

observational_model	Study_Count
Cohort	20
Case Control	6
Case-Only	5
Case-Control	3
NA	2
Other	1

Time Perspective

time_perspective	Study_Count
Prospective	22
Retrospective	11
Cross-Sectional	3
NA	1

Registries

Studies by Country

Country	Study_Count
China	1
Finland	1
Ireland	1
Korea, Republic of	1
Mexico	1
Pakistan	1
United States	1

Sites per Study

Site_count	Study_Count
1	6
2	1

Enrollment Metrics

Measure	Registries
Min	100.0000
1st Qu	170.0000
Median	200.0000
Mean	541.5714
3rd Qu	225.5000
Max	2700.0000

Registry Model

observational_model	Study_Count
Cohort	5
Case-Only	1
Case Control	1

Time Perspective

time_perspective	Study_Count
Prospective	6
Cross-Sectional	1

Follow-up

target_duration	Study_Count
1 Week	1
1 Year	1
2 Years	1
3 Months	1
3 Years	1
6 Months	1
60 Days	1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT02136095	Promising Initial Experience With Intra-operative Fluorescent Cholangiography	https://ClinicalTrials.gov/show/NCT02136095	Completed	Hvidovre University Hospital	2013-12-31
NCT03394807	LaGRA Trial in Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT03394807	Completed	Health Service Executive, Ireland	2017-07-30
NCT02487225	Pentoxifylline Treatment in Acute Pancreatitis (AP)	https://ClinicalTrials.gov/show/NCT02487225	Completed	Mayo Clinic	2017-04-30
NCT03244163	Spyglass DS Peroral Cholangioscope Guided LL or EHL Versus BML for Endoscopic Removal of Complicated Bile Duct Stones	https://ClinicalTrials.gov/show/NCT03244163	Recruiting	Chinese University of Hong Kong	2020-06-30
NCT03180229	Granisetron Effect on Hemodynamic Changes in Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT03180229	Completed	Diskapi Yildirim Beyazit Education and Research Hospital	2017-09-01
NCT03168555	Changes in Bile Acid Homeostasis and Stool Habits After Cholecystectomy	https://ClinicalTrials.gov/show/NCT03168555	Completed	Zealand University Hospital	2019-05-15
NCT03118973	Evaluation of Efficacy and Safety of Goff Transpancreatic Septotomy vs. Double Wire Technique for Achieving Biliary Access in Technically Challenging ERCPs	https://ClinicalTrials.gov/show/NCT03118973	Recruiting	Stanford University	2020-01-01
NCT02947256	Laparoscopic Cholecystectomy With Retro-infundibular Approach	https://ClinicalTrials.gov/show/NCT02947256	Completed	Minia University	2016-01-31
NCT02889471	Routine Nasobiliary Insertion During ERCP in High Risk Patients.	https://ClinicalTrials.gov/show/NCT02889471	Completed	Minia University	2017-08-31
NCT02858986	3D Versus 4K Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT02858986	Completed	Royal Surrey County Hospital NHS Foundation Trust	2017-08-29
NCT02810860	Multimedia Informed Consent & PROMs in Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT02810860	Completed	Nottingham University Hospitals NHS Trust	2018-04-13
NCT02752698	Domestic Surgical Robot Clinical Study	https://ClinicalTrials.gov/show/NCT02752698	Active, not recruiting	The Third Xiangya Hospital of Central South University	2019-12-30
NCT02738710	Comparison of Post-operative Pain at Umbilical Wound After Laparoscopic Cholecystectomy With Transumbilical Versus Infraumbilical Incision	https://ClinicalTrials.gov/show/NCT02738710	Completed	Thammasat University	2017-09-30
NCT02702843	Fluorescent Cholangiography vs White Light for Bile Ducts Identification	https://ClinicalTrials.gov/show/NCT02702843	Completed	The Cleveland Clinic	2017-12-31
NCT02568852	Comparison of Coagulation Factors During Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT02568852	Completed	Lütfiye Nuri Burat Government Hospital	2015-12-31
NCT02558556	FALCON: a Multicenter Randomized Controlled Trial	https://ClinicalTrials.gov/show/NCT02558556	Recruiting	Maastricht University Medical Center	2019-12-31
NCT02490111	Clinical Trials for the Prevention of Gallstone Formation After Gastrectomy in Patient With Gastric Cancer	https://ClinicalTrials.gov/show/NCT02490111	Completed	Daewoong Pharmaceutical Co. LTD.	2018-01-31
NCT02375529	A Trial of Single Incision Versus Four Ports Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT02375529	Completed	Consorci Sanitari Integral	2013-07-31
NCT02363699	Endovenous Lidocaine and Serum Cytokines Concentration	https://ClinicalTrials.gov/show/NCT02363699	Completed	Universidade Federal de Santa Maria	2013-11-30
NCT02357589	3D vs 2D HD Laparoscopy in Cholecystectomy	https://ClinicalTrials.gov/show/NCT02357589	Completed	Helsinki University Central Hospital	2017-05-10
NCT02344654	Fluorescence Cholangiography During Cholecystectomy - a RCT	https://ClinicalTrials.gov/show/NCT02344654	Completed	Hvidovre University Hospital	2018-08-27
NCT02327923	Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT02327923	Completed	B.P. Koirala Institute of Health Sciences	2016-02-29
NCT02317510	Combined Spinal Epidural Anesthesia and General Anesthesia for Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT02317510	Completed	Lütfiye Nuri Burat Government Hospital	2015-02-28
NCT02185586	A Prospective Randomized Controlled Trial of Lower Abdominal Three-port Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT02185586	Completed	China-Japan Friendship Hospital	2015-08-31
NCT02149797	Comparison of “Pick’n Roll” Single-incision Laparoscopic Cholecystectomy Technique, and Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT02149797	Completed	Samsun Education and Research Hospital	2014-04-30
NCT02116985	Dual-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy (DLTCI)	https://ClinicalTrials.gov/show/NCT02116985	Completed	Guangzhou General Hospital of Guangzhou Military Command	2014-10-31
NCT01289379	The Effect of High Frequency Jet Ventilation (HFJV)During Laparoscopic Operations	https://ClinicalTrials.gov/show/NCT01289379	Completed	Western Galilee Hospital-Nahariya	NA
NCT03354065	Inmediate Feeding Tolerance in Acute Pancreatitis	https://ClinicalTrials.gov/show/NCT03354065	Completed	Hospital Central “Dr. Ignacio Morones Prieto”	2017-07-01
NCT01972620	RCT: Multi-modal Analgesia for Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT01972620	Completed	Klinicki Centar Vojvodine	2010-06-30
NCT01881399	Fluorescence Versus Intraoperative Cholangiography in the Visualization of Biliary Tree Anatomy	https://ClinicalTrials.gov/show/NCT01881399	Completed	IHU Strasbourg	2016-06-30
NCT01873638	Comparing Minilaparotomy and Laparoscopic Cholecystectomy as a Day Surgery Procedure	https://ClinicalTrials.gov/show/NCT01873638	Completed	Kuopio University Hospital	2008-04-30
NCT01824186	Trial Comparing Pain in Single-incision Laparoscopic Cholecystectomy Versus Conventional Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT01824186	Completed	National University Hospital, Singapore	2012-10-31
NCT01822262	Contrastive Study for Minimally Invasive Cholecystolithotomy With Gallbladder Reservation and Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT01822262	Recruiting	The First Affiliated Hospital of Guangzhou Medical University	2020-12-31
NCT01685775	Needlescopic Versus Transvaginal/Transumbilical Cholecystectomy	https://ClinicalTrials.gov/show/NCT01685775	Completed	University of Witten/Herdecke	2012-07-31
NCT01683240	Prospective Multicenter Evaluation of a New Short-access-cholangioscope for Biliary Duct Strictures and Gall Stones	https://ClinicalTrials.gov/show/NCT01683240	Completed	Universitätsklinikum Hamburg-Eppendorf	2016-02-29
NCT01678391	Feasibility of Endoscopic Ultrasound Based Biliary Stone Removal Without Fluoroscopy	https://ClinicalTrials.gov/show/NCT01678391	Completed	California Pacific Medical Center Research Institute	2015-06-30
NCT01667848	Warmed, Humidified Carbon Dioxide Insufflation vs Standard Carbon Dioxide in Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT01667848	Completed	Ludwig Boltzmann Institute for Operative Laparoscopy	2013-07-31
NCT01571271	Electrohydraulic Versus Laser Lithotripsy for Treatment of Difficult to Remove Biliary Stones	https://ClinicalTrials.gov/show/NCT01571271	Completed	The Cleveland Clinic	2015-03-31
NCT01558414	Single Incision Laparoscopic Surgery vs Flexible Single Incision Surgery for Cholecystectomy	https://ClinicalTrials.gov/show/NCT01558414	Completed	Hospital Son Llatzer	2011-10-31
NCT01553331	Day Case Laparoscopic Cholecystectomy: Fundus First With Ultrasonic Dissection or Conventional Diathermy Hook	https://ClinicalTrials.gov/show/NCT01553331	Completed	Central Finland Hospital District	2014-10-31
NCT01528722	Randomized Control Trial of Intraperitoneal Bupivacaine During Cholecystectomy	https://ClinicalTrials.gov/show/NCT01528722	Completed	University Hospitals Coventry and Warwickshire NHS Trust	2010-01-31
NCT01492790	Cholecystectomy First vs Sequential Common Bile Duct Imaging + Cholecystectomy	https://ClinicalTrials.gov/show/NCT01492790	Completed	University Hospital, Geneva	2013-02-28
NCT01489436	A Comparison of Single Port and Four Port Laparoscopic Gallbladder Removal	https://ClinicalTrials.gov/show/NCT01489436	Completed	Mayo Clinic	2014-03-31
NCT01410734	Fluorescence Imaging on the da Vinci Surgical System for Intra-operative Near Infrared Imaging of the Biliary Tree (up to 2-weeks Post-operatively)	https://ClinicalTrials.gov/show/NCT01410734	Completed	Intuitive Surgical	2012-12-31
NCT01397565	Minilaparoscopic Versus Conventional Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT01397565	Completed	McGill University Health Centre/Research Institute of the McGill University Health Centre	2015-09-30
NCT00576589	Study Of The Safety And Pharmacokinetics Of CE-326,597 In Patients With Asymptomatic Gallstones	https://ClinicalTrials.gov/show/NCT00576589	Completed	Pfizer	NA
NCT04390828	Effectiveness of Guided Imagery Meditation in Patients With Laparoscopic Gallstone Surgery	https://ClinicalTrials.gov/show/NCT04390828	Recruiting	National Yang-Ming University Hospital	2020-12-31
NCT04350346	The Comparative Analysis Between Motilitone and Gasmotin for the Symptom Relief in Gallstone Patients With Functional Dyspepsia	https://ClinicalTrials.gov/show/NCT04350346	Recruiting	Yonsei University	2020-08-31
NCT04324515	Randomized Trial Comparing Gastric Bypass With and Without Cholecystectomy	https://ClinicalTrials.gov/show/NCT04324515	Recruiting	University of Geneva, Switzerland	2020-08-01
NCT04276285	Laparoscopic Versus US-Guided Subcostal TAP Block After Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT04276285	Recruiting	Mansoura University	2021-02-28
NCT04228835	Does ICG Fluorescence Cholangiography Identify Critical View of Safety Earlier in Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT04228835	Completed	University of Malaya	2019-07-31
NCT04208568	Comparison of Postoperative Pain After Gallbladder Retrieval From Umbilical and Epigastric Ports.	https://ClinicalTrials.gov/show/NCT04208568	Completed	Baqai Medical University	2018-01-31
NCT04183036	Endoclip Papillaplasty Recover Sphincter of Oddi Function After Endoscopic Sphincterotomy for Bile Duct Gallstones	https://ClinicalTrials.gov/show/NCT04183036	Recruiting	Peking University Third Hospital	2019-03-31
NCT02806297	Trial of the Effect of Timing of Cholecystectomy During Initial Admission for Mild Gallstone Pancreatitis	https://ClinicalTrials.gov/show/NCT02806297	Recruiting	The University of Texas Health Science Center, Houston	2018-12-31
NCT04122261	A Clinical Study of Chinese Domestic Surgical Robot	https://ClinicalTrials.gov/show/NCT04122261	Recruiting	The Third Xiangya Hospital of Central South University	2020-10-01
NCT03924804	Effect of Different Infusion Volume on Perioperative Bladder and Blood Volume in Patients Undergoing Daytime Surgery.	https://ClinicalTrials.gov/show/NCT03924804	Recruiting	China Medical University, China	2020-08-30
NCT03909360	Drainage or Not for Laparoscopic Cholecystetomy	https://ClinicalTrials.gov/show/NCT03909360	Recruiting	Second Affiliated Hospital, School of Medicine, Zhejiang University	2020-03-01
NCT03891147	A Clinical Trial of Electro-acupuncture for Treating Gallstone Diseases	https://ClinicalTrials.gov/show/NCT03891147	Recruiting	Chinese University of Hong Kong	2019-06-30
NCT03852836	Evaluation of MRI Sequences for Ultra-rapid Acquisition of Bile Ducts Images	https://ClinicalTrials.gov/show/NCT03852836	Recruiting	IHU Strasbourg	2021-02-28
NCT03812718	Comparison of Anaesthesia Requirement for Ventilation With Endotracheal Tube Versus Proseal Laryngeal Mask Airway	https://ClinicalTrials.gov/show/NCT03812718	Recruiting	Sir Ganga Ram Hospital	2020-12-31
NCT03781687	Bilateral vs. Unilateral Erector Spinae Plane Block	https://ClinicalTrials.gov/show/NCT03781687	Completed	Kocaeli University	2019-06-28
NCT03709030	Early MRI in Acute GallstonE Disease	https://ClinicalTrials.gov/show/NCT03709030	Recruiting	Perspectum Diagnostics Ltd	2020-06-26
NCT03683485	Long-duration EPBD vs EST for Removal of Biliary Stones	https://ClinicalTrials.gov/show/NCT03683485	Recruiting	Dankook University	2019-05-01
NCT03577873	RCT on Necessity of Cholecystectomy for Patients After Clearance of Bile Duct Stones	https://ClinicalTrials.gov/show/NCT03577873	Completed	First People’s Hospital of Hangzhou	2018-02-01
NCT03530241	Fluorescent Cholangiography and Bile Duct Stones	https://ClinicalTrials.gov/show/NCT03530241	Enrolling by invitation	Hvidovre University Hospital	2020-10-31
NCT03442205	Treatment of Common Bile Duct Stones	https://ClinicalTrials.gov/show/NCT03442205	Recruiting	Tongji Hospital	2020-03-01
NCT03429478	Effect of Preoperative Music on Sterile Inflammation Induced by Laparoscopic Surgery	https://ClinicalTrials.gov/show/NCT03429478	Completed	Sir Ganga Ram Hospital	2019-11-30
NCT03422042	Short Duration Versus Fourteen Days Antibiotic in Common Bile Duct Cholangitis	https://ClinicalTrials.gov/show/NCT03422042	Completed	Prince of Songkla University	2019-02-20
NCT03421340	Non-Complex Biliary Stones DSC vs ERC	https://ClinicalTrials.gov/show/NCT03421340	Recruiting	Boston Scientific Corporation	2021-06-30
NCT01211743	Oxidative Stress in Standard Laparoscopic vs Single Port Cholecystectomy	https://ClinicalTrials.gov/show/NCT01211743	Completed	G. Hatzikosta General Hospital	2010-06-30
NCT01199406	Pain Reduction After Cholecystectomy	https://ClinicalTrials.gov/show/NCT01199406	Completed	Meander Medical Center	2010-01-31
NCT01190332	Conventional Versus Rendezvous Technique of Intraoperative Endoscopic Retrograde Cholangiopancreatography	https://ClinicalTrials.gov/show/NCT01190332	Completed	Mansoura University	2010-02-28
NCT01189734	Comparison Between Laparoscopic Common Bile Duct Exploration and Intraoperative ERCP for Management of Common Bile Duct Stones	https://ClinicalTrials.gov/show/NCT01189734	Completed	Mansoura University	NA
NCT01116492	Study of the Inflammatory Reaction in Standard vs Single Port Cholecystectomy for Uncomplicated Cholelithiasis	https://ClinicalTrials.gov/show/NCT01116492	Completed	G. Hatzikosta General Hospital	2010-05-31
NCT01104727	Multi-Port Versus Single-port Cholecystectomy	https://ClinicalTrials.gov/show/NCT01104727	Completed	European Association for Endoscopic Surgery	2015-07-31
NCT01103570	Cholecyst- Versus Cystic Duct Cholangiography During Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT01103570	Completed	Theodor Bilharz Research Institute	2010-01-31
NCT01099319	Renalof in the Treatment of Elderly Patients With Gallstones	https://ClinicalTrials.gov/show/NCT01099319	Completed	Catalysis SL	2011-06-30
NCT01090882	Intraperitoneal Techniques of Local Anaesthesia During Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT01090882	Completed	University Hospitals Coventry and Warwickshire NHS Trust	2009-10-31
NCT01056250	SILS Cholecystectomy: Cholangiography of the Biliary Tract	https://ClinicalTrials.gov/show/NCT01056250	Completed	St John of God Hospital, Vienna	2010-11-30
NCT01047085	Does Cholecystectomy Increase the Esophageal Alkaline Reflux? Evaluation by Impedance-pH Technique	https://ClinicalTrials.gov/show/NCT01047085	Completed	Istanbul University	2009-05-31
NCT01046552	Comparison Between Pre and Intraoperative ERCP in Treatment of Common Bile Duct Stones	https://ClinicalTrials.gov/show/NCT01046552	Completed	Mansoura University	2009-07-31
NCT01009450	Clipless Laparoscopic Cholecystectomy Using Harmonic Scalpel in Cirrhotic Patients a Prospective Randomized Study	https://ClinicalTrials.gov/show/NCT01009450	Completed	Mansoura University	2009-10-31
NCT00984100	Natural Orifice Translumenal Endoscopic Surgery (NOTES) Transvaginal Cholecystectomy	https://ClinicalTrials.gov/show/NCT00984100	Completed	Baystate Medical Center	2015-01-31
NCT00981604	Single Incision Laparoscopic Surgery (SILS) Versus Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT00981604	Completed	Children’s Mercy Hospital Kansas City	2011-08-31
NCT00974194	Safety and Cost-effectiveness Study of Single Port Laparoscopic Cholecystectomies	https://ClinicalTrials.gov/show/NCT00974194	Completed	University of Lausanne Hospitals	2017-09-01
NCT00986544	Drain After Elective Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT00986544	Completed	University of Roma La Sapienza	2011-02-28
NCT00886210	Clinical Impact of Routine Abdominal Drainage After Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT00886210	Completed	Mansoura University	2008-03-31
NCT00863642	Early Versus Delayed Surgery for Gallstone Pancreatitis	https://ClinicalTrials.gov/show/NCT00863642	Completed	Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center	2009-11-30
NCT03774589	Bilioenteric Anastomosis by Magnetic Compressive Technique	https://ClinicalTrials.gov/show/NCT03774589	Recruiting	First Affiliated Hospital Xi’an Jiaotong University	2021-01-31
NCT01625026	Obeticholic Acid in Bariatric and Gallstone Disease	https://ClinicalTrials.gov/show/NCT01625026	Completed	Sahlgrenska University Hospital, Sweden	2016-04-30
NCT02909595	Balloon Catheter vs. Basket Catheter for Endoscopic Bile Duct Stone Extraction	https://ClinicalTrials.gov/show/NCT02909595	Completed	Anhui Provincial Hospital	2016-11-30
NCT02351492	Radiological Investigation of Bile Duct Obstruction	https://ClinicalTrials.gov/show/NCT02351492	Recruiting	University Hospital, Basel, Switzerland	2020-08-31
NCT02394327	Endoscopic Nasogallbladder Drainage Versus Gallbladder Stenting Before Cholecystecomy	https://ClinicalTrials.gov/show/NCT02394327	Completed	Ajou University School of Medicine	2014-12-31
NCT01424215	The Use of Fluorescent Imaging for Intraoperative Cholangiogram During Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT01424215	Completed	Maimonides Medical Center	2014-08-31
NCT00835250	Laparoscopic Cholecystectomy vs Hybrid Natural Orifice Translumenal Surgery	https://ClinicalTrials.gov/show/NCT00835250	Completed	Hospital Son Llatzer	2011-05-31
NCT00807729	Randomized Trial of ERCP Then Laparoscopic Cholecystectomy vs. Laparoscopic Cholecystectomy Plus Laparoscopic Common Bile Duct Exploration in Patients With Likely Choledocholithiasis	https://ClinicalTrials.gov/show/NCT00807729	Completed	University of California, San Francisco	2003-07-31
NCT00711581	Evaluation of Laparoscopic Internal Retractor Device	https://ClinicalTrials.gov/show/NCT00711581	Completed	Hadassah Medical Organization	2011-06-30
NCT00710502	Transvaginal NOTES Cholecystectomy: Phase I/II Mexico Clinical Trial	https://ClinicalTrials.gov/show/NCT00710502	Completed	North Texas Veterans Healthcare System	2009-12-31
NCT00678873	Single Incision Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT00678873	Completed	North Texas Veterans Healthcare System	2009-12-31
NCT00674713	Effect of Acupuncture on Postoperative Nausea and Vomiting	https://ClinicalTrials.gov/show/NCT00674713	Completed	Catholic University of the Sacred Heart	2007-09-30
NCT00616616	Single Incision Laparoscopy	https://ClinicalTrials.gov/show/NCT00616616	Completed	University of California, San Diego	2009-07-31
NCT00606762	Comparison Between Low Pressure Versus High Pressure Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT00606762	Completed	Sterling Hospital	2007-11-30
NCT00562900	Robotic Assisted Versus Laparoscopic Cholecystectomy - Outcome and Cost Analyses of a Case-Matched Control Study	https://ClinicalTrials.gov/show/NCT00562900	Completed	University of Zurich	NA
NCT00370344	Small-incision Open Cholecystectomy or Laparoscopic Cholecystectomy for Gallbladder Disease	https://ClinicalTrials.gov/show/NCT00370344	Completed	Umeå University	2011-04-30
NCT00164853	Compare Combined Sphincterotomy and Balloon Dilation (ESBD) Versus Standard Sphincterotomy (ES) in Removing Biliary Stones	https://ClinicalTrials.gov/show/NCT00164853	Completed	Chinese University of Hong Kong	2011-09-30
NCT00161083	UDCA for Symptomatic Gallstone Disease	https://ClinicalTrials.gov/show/NCT00161083	Completed	UMC Utrecht	NA
NCT00131131	Epidemiology of Gallbladder Sludge and Stones in Pregnancy	https://ClinicalTrials.gov/show/NCT00131131	Completed	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	2008-11-30
NCT00836316	Levobupivacaine During Cholecystectomy	https://ClinicalTrials.gov/show/NCT00836316	Completed	Ege University	NA

Observational Studiess

#If less then 500 studies

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03193177	A Retrospective and Prospective Cohort Study of the 21-day Fasting-like Diet in Patients With Metabolic and Autoimmune Diseases	https://ClinicalTrials.gov/show/NCT03193177	Completed	Tsinghua University	2018-08-31
NCT03154164	Study on the Learning Curve for Fundus First With Ultrasonic Tissue Coagulation in Elective Cholecystectomy	https://ClinicalTrials.gov/show/NCT03154164	Completed	Karolinska Institutet	2019-12-31
NCT03059745	Use of Robotics for Cholecystectomy; Retrospective Review of Outcomes, Set Up and Learning Curves	https://ClinicalTrials.gov/show/NCT03059745	Completed	University of California, Davis	2017-03-03
NCT02831556	Point of Care 3D Ultrasound for Various Applications: A Pilot Study	https://ClinicalTrials.gov/show/NCT02831556	Recruiting	Duke University	2025-01-31
NCT02808546	The Risk Factors of Symptomatic Gallbladder Stone: Age-Sex Matched Case-control Study Performed in Single Institute	https://ClinicalTrials.gov/show/NCT02808546	Completed	Cheju Halla General Hospital	2013-12-31
NCT02697149	Nonradiation-to-endoscopist Endoscopic Retrograde Cholangiopancreatography in Patients With Complexity Level I/II	https://ClinicalTrials.gov/show/NCT02697149	Completed	Fourth Military Medical University	2016-04-30
NCT02682368	Multicentric Point of Care UltraSound by Surgeons Trial	https://ClinicalTrials.gov/show/NCT02682368	Completed	Connolly Hospital Blanchardstown	2019-04-30
NCT02667249	Compliance of Clinical Pathways in Elective Laparoscopic Cholecystectomy: Evaluation of Different Implementation Methods	https://ClinicalTrials.gov/show/NCT02667249	Completed	University Hospital Tuebingen	2013-04-30
NCT02654873	Is Routine Use of Histopathological Examination Necessary After Cholecystectomy ?	https://ClinicalTrials.gov/show/NCT02654873	Completed	Sisli Hamidiye Etfal Training and Research Hospital	2017-10-31
NCT02469935	Accuracy of Surgeon-performed Ultrasound in Detecting Gallstones - a Validation Study	https://ClinicalTrials.gov/show/NCT02469935	Completed	Karolinska Institutet	2012-11-30
NCT02349568	The Cost Effectiveness of Endoscopic Ultrasound ( EUS ) Based Strategy in Diagnosis of Common Bile Duct Stones	https://ClinicalTrials.gov/show/NCT02349568	Completed	Prince of Songkla University	2013-12-31
NCT02329977	Rate of Duodenal-biliary Reflux Increases in Patients With Recurrent Common Bile Duct Stones	https://ClinicalTrials.gov/show/NCT02329977	Completed	Fourth Military Medical University	2013-12-31
NCT01855308	Single Site Robotic Cholecystectomy in Non Selected Patients	https://ClinicalTrials.gov/show/NCT01855308	Completed	University of California, Davis	2017-01-31
NCT01740973	Risk of Umbilical Trocar-site Hernia After SILC Cholecystectomy Versus Conventional Cholecystectomy	https://ClinicalTrials.gov/show/NCT01740973	Completed	Hvidovre University Hospital	2014-09-30
NCT01734720	Common Bile Duct Stones - Natural History and Interventions	https://ClinicalTrials.gov/show/NCT01734720	Completed	Karolinska Institutet	2009-12-31
NCT01707121	The Impact of Physical Activity on the Outcome of Surgery	https://ClinicalTrials.gov/show/NCT01707121	Completed	Sahlgrenska University Hospital, Sweden	2015-09-30
NCT03326154	Post-Cholecystectomy Quality of Life	https://ClinicalTrials.gov/show/NCT03326154	Recruiting	Helsinki University Central Hospital	2020-09-01
NCT04308993	Percutaneous Endoscopic Biliary Exploration in Complex Biliary Stone Disease	https://ClinicalTrials.gov/show/NCT04308993	Completed	Imam Abdulrahman Bin Faisal University	2016-08-31
NCT04250402	The Incidence of Gallstones After Gastric Cancer Surgery	https://ClinicalTrials.gov/show/NCT04250402	Recruiting	Hepatopancreatobiliary Surgery Institute of Gansu Province	2021-02-10
NCT04213092	Single Setting ERCP and Laparoscopic Cholecystectomy is a Safe Procedure in Patients With Cholecysto-Choledocholithiasis	https://ClinicalTrials.gov/show/NCT04213092	Completed	Lumbini Medical College	2015-10-31
NCT04145843	Treatment Outcomes in Bile Duct Stones	https://ClinicalTrials.gov/show/NCT04145843	Recruiting	AdventHealth	2020-12-31
NCT04025645	Common Bile Duct Pressures in Patients With and Without Cholelithiasis	https://ClinicalTrials.gov/show/NCT04025645	Completed	Hospital de La Serena	2017-06-30
NCT03888976	Cholecystoduodenal Fistula With and Without Gallstone Ileus	https://ClinicalTrials.gov/show/NCT03888976	Completed	Tecnologico de Monterrey	2019-02-26
NCT03809559	Repeatability and Reproducibility of Quantitative MRCP	https://ClinicalTrials.gov/show/NCT03809559	Completed	Perspectum Diagnostics Ltd	2018-09-08
NCT03804775	Comparative Analysis of Serum Lipid Profiles in Patients With and Without Gallstones	https://ClinicalTrials.gov/show/NCT03804775	Completed	Services Hospital, Lahore	2018-08-30
NCT03768661	Incisional Hernia Rate After Single-incision Laparoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT03768661	Completed	Hospital Plató	2011-06-30
NCT03470584	Vegetarian Diet and Chronic Degenerative Diseases	https://ClinicalTrials.gov/show/NCT03470584	Completed	Dalin Tzu Chi General Hospital	2005-12-30
NCT01190280	Indications for Gallbladder Surgery in Gallstone Disease	https://ClinicalTrials.gov/show/NCT01190280	Completed	Haraldsplass Deaconess Hospital	2010-08-31
NCT01139385	Clipless Laparoscopic Cholecystectomy Using Harmonic Scalpel Versus Conventional Method in Day Surgery	https://ClinicalTrials.gov/show/NCT01139385	Completed	University of Roma La Sapienza	2014-02-28
NCT01117415	Cost Effectiveness Analysis of Cholecystectomy, Projected Long Term Outcomes and Complications Evaluation	https://ClinicalTrials.gov/show/NCT01117415	Completed	University Hospitals Cleveland Medical Center	2010-06-30
NCT00971750	Laparoscopic Versus Transabdominal Ultrasound in Morbidly Obese Patients	https://ClinicalTrials.gov/show/NCT00971750	Completed	Gundersen Lutheran Medical Foundation	2010-10-31
NCT00940264	Laparoscopic Transvaginal Hybrid Cholecystectomy: a Prospective Data Collection.	https://ClinicalTrials.gov/show/NCT00940264	Completed	Cantonal Hospital of St. Gallen	2011-04-30
NCT00890201	Pancreaticobiliary Reflux in Patients Without Cholelithiasis	https://ClinicalTrials.gov/show/NCT00890201	Completed	Cirujanos la Serena	2009-07-31
NCT04142203	Implementation of 23 Hour Surgery Model in a Tertiary Hospital	https://ClinicalTrials.gov/show/NCT04142203	Active, not recruiting	Kuopio University Hospital	2020-05-30
NCT01583348	Technical Feasibility of Routine Intraoperative Cholangiography During Elective Rigid-hybrid Transvaginal Natural Orifice Transluminal Endoscopic Cholecystectomy	https://ClinicalTrials.gov/show/NCT01583348	Completed	Cantonal Hosptal, Baselland	2012-10-31
NCT00530998	Minimally Invasive Surgery: Using Natural Orfices	https://ClinicalTrials.gov/show/NCT00530998	Completed	University of California, San Diego	2019-09-30
NCT00528632	Gallbladder Cholesterolosis, Body Mass Index and Serum Cholesterol and Triglycerides	https://ClinicalTrials.gov/show/NCT00528632	Completed	Cirujanos la Serena	2009-06-30

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT01829139	Efficacy of Choleretics in Acalculous Gallbladder in Situ After Endoscopic Removal of Biliary Stones	https://ClinicalTrials.gov/show/NCT01829139	Recruiting	Soon Chun Hyang University	2014-02-28
NCT04410848	Symbolic Regression Model To Predict Choledocholithiasis	https://ClinicalTrials.gov/show/NCT04410848	Recruiting	Hospital Universitario Dr. Jose E. Gonzalez	2020-05-30
NCT04052633	Success of Intraoperative Cholangiography	https://ClinicalTrials.gov/show/NCT04052633	Completed	Jyväskylä Central Hospital	2019-03-26
NCT03610308	ESTES Snapshot Audit 2018	https://ClinicalTrials.gov/show/NCT03610308	Completed	European Socierty for Trauma and Emergency Surgery	2018-12-31
NCT03594409	Frequency of Patho-morphological Classes of Gall Stones in Lahore, Pakistan	https://ClinicalTrials.gov/show/NCT03594409	Completed	Services Hospital, Lahore	2018-06-30
NCT03482375	Prospective Evaluation of Residual Bile Duct Stone by Peroral Cholangioscopy After Conventional ERCP	https://ClinicalTrials.gov/show/NCT03482375	Completed	Northwell Health	2018-10-30
NCT02554097	Chinese Registry Study on Treatment of Cholecysto-Choledocholithiasis	https://ClinicalTrials.gov/show/NCT02554097	Active, not recruiting	Beijing Friendship Hospital	2018-12-15